Pharmaceutical Organic Chemistry Syllabus PDF | B.Pharm 2nd Semester | Old Syllabus

Pharmaceutical Organic Chemistry syllabus for 2nd Semester. This page presents the detailed syllabus content from the original Old Syllabus PDF.

About This Syllabus

• Classification, nomenclature and isomerism
Classification of Organic Compounds
Common and IUPAC systems of nomenclature of organic compounds
(up to 10 Carbons open chain and carbocyclic compounds)
Structural isomerisms in organic compounds

Course Syllabus

Unit-I • Classification, Nomenclature And Isomerism

Classification of Organic Compounds Common and IUPAC systems of nomenclature of organic compounds (up to 10 Carbons open chain and carbocyclic compounds) Structural isomerisms in organic compounds

Unit-Ii • Alkanes*, Alkenes* And Conjugated Dienes*

SP3 hybridization in alkanes, Halogenation of alkanes, uses of paraffins. Stabilities of alkenes, SP2 hybridization in alkenes E1 and E2 reactions – kinetics, order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeffs orientation and evidences. E1 verses E2 reactions, Factors affecting E1 and E2 reactions. Ozonolysis, electrophilic addition reactions of alkenes, Markownikoff’s orientation, free radical addition reactions of alkenes, Anti Markownikoff’s orientation. Stability of conjugated dienes, Diel-Alder, electrophilic addition, free radical addition reactions of conjugated dienes, allylic rearrangement

Unit-Iii • Alkyl Halides*

SN1 and SN2 reactions – kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations. SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions Structure and uses of ethylchloride, Chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform.

• Alcohols*- Qualitative tests, Structure and uses of Ethyl alcohol, Methyl

alcohol, chlorobutanol, Cetosteryl alcohol, Benzyl alcohol, Glycerol, Propylene glycol

Unit-Iv • Carbonyl Compounds* (Aldehydes And Ketones)

Nucleophilic addition, Electromeric effect, aldol condensation, Crossed Aldol condensation, Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation, Perkin condensation, qualitative tests, Structure and uses of Formaldehyde, Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin, Cinnamaldehyde.

Unit-V • Carboxylic Acids*

Acidity of carboxylic acids, effect of substituents on acidity, inductive effect and qualitative tests for carboxylic acids ,amide and ester Structure and Uses of Acetic acid, Lactic acid, Tartaric acid, Citric acid, Succinic acid. Oxalic acid, Salicylic acid, Benzoic acid, Benzyl benzoate, Dimethyl phthalate, Methyl salicylate and Acetyl salicylic acid

• Aliphatic amines* – Basicity, effect of substituent on Basicity. Qualitative

test, Structure and uses of Ethanolamine, Ethylenediamine, Amphetamine BP208P. PHARMACEUTICAL ORGANIC CHEMISTRY -I (Practical 1. Systematic qualitative analysis of unknown organic compounds like

• Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation

and unsaturation, etc.

• Detection of elements like Nitrogen, Sulphur and Halogen by

Lassaigne’s test

• Solubility test
• Functional group test like Phenols, Amides/ Urea, Carbohydrates,

Amines, Carboxylic acids, Aldehydes and Ketones, Alcohols, Esters, Aromatic and Halogenated Hydrocarbons, Nitro compounds and Anilides.

• Melting point/Boiling point of organic compounds
• Identification of the unknown compound from the literature using

melting point/ boiling point.

• Preparation of the derivatives and confirmation of the unknown

compound by melting point/ boiling point.

• Minimum 5 unknown organic compounds to be analysed systematically.

2. Preparation of suitable solid derivatives from organic compounds 3. Construction of molecular models

Practical Syllabus

1. Systematic qualitative analysis of unknown organic compounds like
2. Preparation of suitable solid derivatives from organic compounds
3. Construction of molecular models

The original syllabus PDF is available below for students who want to download and refer to the complete document.