Pharmaceutical Organic Chemistry Syllabus PDF | B.Pharm 3rd Semester | Old Syllabus

Pharmaceutical Organic Chemistry syllabus for 3rd Semester. This page presents the detailed syllabus content from the original Old Syllabus PDF.

About This Syllabus

A. Analytical, synthetic and other evidences in the derivation of structure
of benzene, Orbital picture, resonance in benzene, aromatic
characters, Huckel’s rule

Course Syllabus

Unit I • Benzene And Its Derivatives

A. Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel’s rule B. Reactions of benzene – nitration, sulphonation, halogenation reactivity, Friedelcrafts alkylation- reactivity, limitations, Friedelcrafts acylation. C. Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction D. Structure and uses of DDT, Saccharin, BHC and Chloramine

Unit Ii • Phenols* – Acidity Of Phenols, Effect Of Substituents On Acidity, Qualitative

tests, Structure and uses of phenol, cresols, resorcinol, naphthols

• Aromatic Amines* – Basicity of amines, effect of substituents on basicity,

and synthetic uses of aryl diazonium salts

• Aromatic Acids* –Acidity, effect of substituents on acidity and

important reactions of benzoic acid.

Unit Iii • Fats And Oils

a.Fatty acids – reactions. b. Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils. c. Analytical constants – Acid value, Saponification value, Ester value, Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and principle involved in their determination.

Unit Iv • Polynuclear Hydrocarbons:

a. Synthesis, reactions b. Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives

Unit V • Cyclo Alkanes*

Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only BP305P. PHARMACEUTICAL ORGANIC CHEMISTRY -II (Practical) I Experiments involving laboratory techniques

• Recrystallization
• Steam distillation

II Determination of following oil values (including standardization of reagents)

• Acid value
• Saponification value
• Iodine value

III Preparation of compounds

• Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol

/Aniline by acylation reaction.

• 2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline/
• Acetanilide by halogenation (Bromination) reaction.
• 5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid /

Nitro benzene by nitration reaction.

• Benzoic acid from Benzyl chloride by oxidation reaction.
• Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by

hydrolysis reaction.

• 1-Phenyl azo-2-napthol from Aniline by diazotization and coupling

reactions.

• Benzil from Benzoin by oxidation reaction.
• Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction
• Cinnammic acid from Benzaldehyde by Perkin reaction
• P-Iodo benzoic acid from P-amino benzoic acid

Practical Syllabus

BP305P. PHARMACEUTICAL ORGANIC CHEMISTRY -II (Practical)

I Experiments involving laboratory techniques

• Recrystallization • Steam distillation

II Determination of following oil values (including standardization of reagents)

• Acid value • Saponification value • Iodine value

III Preparation of compounds

• Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol /Aniline by acylation reaction. • 2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline/ • Acetanilide by halogenation (Bromination) reaction. • 5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid / Nitro benzene by nitration reaction. • Benzoic acid from Benzyl chloride by oxidation reaction. • Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by

hydrolysis reaction. • 1-Phenyl azo-2-napthol from Aniline by diazotization and coupling reactions. • Benzil from Benzoin by oxidation reaction. • Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction • Cinnammic acid from Benzaldehyde by Perkin reaction • P-Iodo benzoic acid from P-amino benzoic acid

The original syllabus PDF is available below for students who want to download and refer to the complete document.