Pharmaceutical Organic Chemistry Iii Syllabus PDF | B.Pharm 4th Semester | Old Syllabus

Pharmaceutical Organic Chemistry Iii syllabus for 4th Semester. This page presents the detailed syllabus content from the original Old Syllabus PDF.

About This Syllabus

Stereo isomerism
Optical isomerism –
Optical activity, enantiomerism, distereo isomerism, meso compounds
Elements of symmetry, chiral and achiral molecules
DL system of nomenclature of optical isomers, sequence rules, RS system of
nomenclature of optical isomers
Reactions of chiral molecules
Racemic modification and resolution of racemic mixture.
Asymmetric synthesis: partial and absolute

Course Syllabus

Unit-I Stereo Isomerism

Optical isomerism – Optical activity, enantiomerism, distereo isomerism, meso compounds Elements of symmetry, chiral and achiral molecules DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers Reactions of chiral molecules Racemic modification and resolution of racemic mixture. Asymmetric synthesis: partial and absolute

Unit-Ii Geometrical Isomerism

Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems) Methods of determination of configuration of geometrical isomers. Conformational isomerism in Ethane, n-Butane and Cyclohexane. Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity. Stereospecific and stereoselective reactions

Unit-Iii Heterocyclic Compounds:

Nomenclature and classification Synthesis, reactions and medicinal uses of following compounds/derivatives Pyrrole, Furan, and Thiophene Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene

Unit-Iv Synthesis, Reactions And Medicinal Uses Of Following Compounds/Derivatives

Pyrazole, Imidazole, Oxazole and Thiazole. Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives

Unit-V Reactions Of Synthetic Importance

Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch reduction, Wolff Kishner reduction. Oppenauer-oxidation and Dakin reaction. Beckmanns rearrangement and Schmidt rearrangement. Claisen-Schmidt condensation

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