Physical Pharmaceutics Ii Syllabus PDF | B.Pharm 4th Semester | Old Syllabus

Physical Pharmaceutics Ii syllabus for 4th Semester. This page presents the detailed syllabus content from the original Old Syllabus PDF.

About This Syllabus

Colloidal dispersions: Classification of dispersed systems & their general
characteristics, size & shapes of colloidal particles, classification of colloids &
comparative account of their general properties. Optical, kinetic & electrical
properties.
Effect of electrolytes, coacervation, peptization& protective action.

Course Syllabus

Unit-I Colloidal Dispersions: Classification Of Dispersed Systems & Their General

characteristics, size & shapes of colloidal particles, classification of colloids & comparative account of their general properties. Optical, kinetic & electrical properties. Effect of electrolytes, coacervation, peptization& protective action.

Unit-Ii Rheology: Newtonian Systems, Law Of Flow, Kinematic Viscosity, Effect Of

temperature, non-Newtonian systems, pseudoplastic, dilatant, plastic, thixotropy, thixotropy in formulation, determination of viscosity, capillary, falling Sphere, rotational viscometers Deformation of solids: Plastic and elastic deformation, Heckel equation, Stress, Strain, Elastic Modulus

Unit-Iii Coarse Dispersion: Suspension, Interfacial Properties Of Suspended Particles,

settling in suspensions, formulation of flocculated and deflocculated suspensions. Emulsions and theories of emulsification, microemulsion and multiple emulsions; Stability of emulsions, preservation of emulsions, rheological properties of emulsions and emulsion formulation by HLB method.

Unit-Iv Micromeretics: Particle Size And Distribution, Mean Particle Size, Number And

weight distribution, particle number, methods for determining particle size by different methods, counting and separation method, particle shape, specific surface, methods for determining surface area, permeability, adsorption, derived properties of powders, porosity, packing arrangement, densities, bulkiness & flow properties.

Unit-V Drug Stability: Reaction Kinetics: Zero, Pseudo-Zero, First & Second Order, Units

of basic rate constants, determination of reaction order. Physical and chemical factors influencing the chemical degradation of pharmaceutical product: temperature, solvent, ionic strength, dielectric constant, specific & general acid base catalysis, Simple numerical problems. Stabilization of medicinal agents against common reactions like hydrolysis & oxidation. Accelerated stability testing in expiration dating of pharmaceutical dosage forms. Photolytic degradation and its prevention BP 407P. PHYSICAL PHARMACEUTICS- II (Practical) 1. Determination of particle size, particle size distribution using sieving method 2. Determination of particle size, particle size distribution using Microscopic

method 3. Determination of bulk density, true density and porosity 4. Determine the angle of repose and influence of lubricant on angle of repose 5. Determination of viscosity of liquid using Ostwald’s viscometer 6. Determination sedimentation volume with effect of different suspending agent 7. Determination sedimentation volume with effect of different concentration of single suspending agent 8. Determination of viscosity of semisolid by using Brookfield viscometer 9. Determination of reaction rate constant first order. 10. Determination of reaction rate constant second order 11. Accelerated stability studies

Practical Syllabus

1. Determination of particle size, particle size distribution using sieving method
2. Determination of particle size, particle size distribution using Microscopic
3. Determination of bulk density, true density and porosity
4. Determine the angle of repose and influence of lubricant on angle of repose
5. Determination of viscosity of liquid using Ostwald’s viscometer
6. Determination sedimentation volume with effect of different suspending
7. Determination sedimentation volume with effect of different concentration of
8. Determination of viscosity of semisolid by using Brookfield viscometer
9. Determination of reaction rate constant first order.
10. Determination of reaction rate constant second order
11. Accelerated stability studies

The original syllabus PDF is available below for students who want to download and refer to the complete document.